Plasma riche en plaquettes, 2 séances face à Fraction vasculaire stromale adipeuse mêlée au PRP, 2 séances à 4 semaines
1 essai les comparent directement, sur les mêmes patients. Voir Plasma riche en plaquettes, 2 séances · Voir Fraction vasculaire stromale adipeuse mêlée au PRP, 2 séances à 4 semaines
Un seul petit essai de fiabilité limitée, chez 22 adultes atteints d'alopécie androgénétique, a comparé le PRP seul au PRP mêlé à de la fraction vasculaire stromale adipeuse, chacun en 2 séances (Butt 2020). À 30 semaines, le mélange fait nettement mieux : la densité gagne +51,64 % contre +21,51 % avec le PRP seul, le nombre de cheveux passant de 37,66 à 57,11 par cm² contre de 52,44 à 63,72. Ce résultat isolé reste à confirmer.
Butt 2020
Essai randomisé, risque de biais élevé. Stromal vascular fraction-enriched platelet-rich plasma therapy reverses the effects of androgenetic alopecia.
| Critère | Plasma riche en plaquettes, 2 séances | Fraction vasculaire stromale adipeuse mêlée au PRP, 2 séances à 4 semaines | Écart |
|---|---|---|---|
| Densité capillaire totale | 52,44 → 63,72 cheveux par cm² à un mois d'intervalleVoir la citationMean density of hair in PRP group on FIGURE 2 Hair density before and after PRP therapy and SVF‐PRP therapy. A, showing representative trichoscan image. B, Hair density in both groups before injection and at 6 mo after injection of PRP or SVF‐PRP. C, D, showing percentage increase in hair density 6 mo after injections of either PRP alone or a combination of SVF and PRP. PRP, platelet‐rich plasma; SVF, stromal vascular fraction BUTT al. eT first visit was 52.44 ± 9.66, and it was 37.66 ± 7.43 in SVF‐PRP group. On final visit (after 6 months of last session), it was 63.72 ± 11.68 in PRP group and 57.11 ± 7.73 in the SVF‐PRP group. Overall, the per‐ centage increase in PRP group was 21.51% as compared to SVF‐PRP group in which there was 51.64% increase (P‐value .006). Butt G, Hussain I, Ahmad FJ et al.. Stromal vascular fraction-enriched platelet-rich plasma therapy reverses the effects of androgenetic alopecia.. J Cosmet Dermatol 2020, DOI 10.1111/jocd.13149. Citation reproduite au titre du droit de courte citation (article L122-5 du Code de la propriété intellectuelle). | 37,66 → 57,11 cheveux par cm²Voir la citationMean density of hair in PRP group on FIGURE 2 Hair density before and after PRP therapy and SVF‐PRP therapy. A, showing representative trichoscan image. B, Hair density in both groups before injection and at 6 mo after injection of PRP or SVF‐PRP. C, D, showing percentage increase in hair density 6 mo after injections of either PRP alone or a combination of SVF and PRP. PRP, platelet‐rich plasma; SVF, stromal vascular fraction BUTT al. eT first visit was 52.44 ± 9.66, and it was 37.66 ± 7.43 in SVF‐PRP group. On final visit (after 6 months of last session), it was 63.72 ± 11.68 in PRP group and 57.11 ± 7.73 in the SVF‐PRP group. Overall, the per‐ centage increase in PRP group was 21.51% as compared to SVF‐PRP group in which there was 51.64% increase (P‐value .006). Butt G, Hussain I, Ahmad FJ et al.. Stromal vascular fraction-enriched platelet-rich plasma therapy reverses the effects of androgenetic alopecia.. J Cosmet Dermatol 2020, DOI 10.1111/jocd.13149. Citation reproduite au titre du droit de courte citation (article L122-5 du Code de la propriété intellectuelle). | Probablement réel |
| Variation relative de densité | +21,51 % à un mois d'intervalleVoir la citationMean density of hair in PRP group on FIGURE 2 Hair density before and after PRP therapy and SVF‐PRP therapy. A, showing representative trichoscan image. B, Hair density in both groups before injection and at 6 mo after injection of PRP or SVF‐PRP. C, D, showing percentage increase in hair density 6 mo after injections of either PRP alone or a combination of SVF and PRP. PRP, platelet‐rich plasma; SVF, stromal vascular fraction BUTT al. eT first visit was 52.44 ± 9.66, and it was 37.66 ± 7.43 in SVF‐PRP group. On final visit (after 6 months of last session), it was 63.72 ± 11.68 in PRP group and 57.11 ± 7.73 in the SVF‐PRP group. Overall, the per‐ centage increase in PRP group was 21.51% as compared to SVF‐PRP group in which there was 51.64% increase (P‐value .006). Butt G, Hussain I, Ahmad FJ et al.. Stromal vascular fraction-enriched platelet-rich plasma therapy reverses the effects of androgenetic alopecia.. J Cosmet Dermatol 2020, DOI 10.1111/jocd.13149. Citation reproduite au titre du droit de courte citation (article L122-5 du Code de la propriété intellectuelle). | +51,64 %Voir la citationMean density of hair in PRP group on FIGURE 2 Hair density before and after PRP therapy and SVF‐PRP therapy. A, showing representative trichoscan image. B, Hair density in both groups before injection and at 6 mo after injection of PRP or SVF‐PRP. C, D, showing percentage increase in hair density 6 mo after injections of either PRP alone or a combination of SVF and PRP. PRP, platelet‐rich plasma; SVF, stromal vascular fraction BUTT al. eT first visit was 52.44 ± 9.66, and it was 37.66 ± 7.43 in SVF‐PRP group. On final visit (after 6 months of last session), it was 63.72 ± 11.68 in PRP group and 57.11 ± 7.73 in the SVF‐PRP group. Overall, the per‐ centage increase in PRP group was 21.51% as compared to SVF‐PRP group in which there was 51.64% increase (P‐value .006). Butt G, Hussain I, Ahmad FJ et al.. Stromal vascular fraction-enriched platelet-rich plasma therapy reverses the effects of androgenetic alopecia.. J Cosmet Dermatol 2020, DOI 10.1111/jocd.13149. Citation reproduite au titre du droit de courte citation (article L122-5 du Code de la propriété intellectuelle). | Probablement réel |