Exosomes de cellules stromales mésenchymateuses, injection unique de 3 mL

pared to pre-treatment (p\0.05). The mean hair density increased from 149.7 ± 13.7 hairs/cm2 at pre-treatment to 153.6 ± 16.8 hairs/cm2 at the 4th week (p = 0.043) and further to 157 ± 18.3 hairs/cm2 at the 12th week (p = 0.002).

Citation complémentaire (inclusion)

This prospective study included 30 male patients, aged between 22 and 65, with hair type III–VI according to the Norwood-Hamilton scale. They agreed not to change their hairstyleandwouldnotundergoanyhaircareortreatment

Citation complémentaire (methode)

vertex points) were taken. After the imaging, the applica- tionwasperformed:Atotalof3 mLofexosomes(2 mLto the frontal and 1 mL to the vertex region) was injected using the napage technique (1010 extracellular vesicles in 1 mL). Patients were observed for possibleside effects for 1 h after the procedure. Patients were instructed not to wash their hair and avoid heavy activities for 1 day after

Citation complémentaire (population)

To ensure measurements from the same point during con- trols, some topographic points were determined. For 2 points in the frontal region, the points within 5 cm of the hairline at the left and right mid-pupil lines were consid- ered,andfortheonepointatthevertex,2 cmmedialtothe hair whorl was taken as the basis. An area of 1 cm2 from each of the mentioned areas was selected, and 9 40 magnificationimagesofthoseareasweretakenwithdigital dermatoscopy (MoleMax HD, Derma Medical Systems, Austria). These dermatoscopic images recorded hair den- sities(haircount/cm2)withTrichoscan(TrichoLabGmbH, Germany).Theaveragevaluesof3regions(2frontaland1

Ersan M, Ozer E, Akin O et al.. Effectiveness of exosome treatment in androgenetic alopecia: outcomes of a prospective study. Aesthetic Plastic Surgery 2024, DOI 10.1007/s00266-024-04332-3. Citation sous licence CC-BY.

pared to pre-treatment (p\0.05). The mean hair density increased from 149.7 ± 13.7 hairs/cm2 at pre-treatment to 153.6 ± 16.8 hairs/cm2 at the 4th week (p = 0.043) and further to 157 ± 18.3 hairs/cm2 at the 12th week (p = 0.002).

Citation complémentaire (inclusion)

This prospective study included 30 male patients, aged between 22 and 65, with hair type III–VI according to the Norwood-Hamilton scale. They agreed not to change their hairstyleandwouldnotundergoanyhaircareortreatment

Citation complémentaire (methode)

vertex points) were taken. After the imaging, the applica- tionwasperformed:Atotalof3 mLofexosomes(2 mLto the frontal and 1 mL to the vertex region) was injected using the napage technique (1010 extracellular vesicles in 1 mL). Patients were observed for possibleside effects for 1 h after the procedure. Patients were instructed not to wash their hair and avoid heavy activities for 1 day after

Citation complémentaire (population)

To ensure measurements from the same point during con- trols, some topographic points were determined. For 2 points in the frontal region, the points within 5 cm of the hairline at the left and right mid-pupil lines were consid- ered,andfortheonepointatthevertex,2 cmmedialtothe hair whorl was taken as the basis. An area of 1 cm2 from each of the mentioned areas was selected, and 9 40 magnificationimagesofthoseareasweretakenwithdigital dermatoscopy (MoleMax HD, Derma Medical Systems, Austria). These dermatoscopic images recorded hair den- sities(haircount/cm2)withTrichoscan(TrichoLabGmbH, Germany).Theaveragevaluesof3regions(2frontaland1

Ersan M, Ozer E, Akin O et al.. Effectiveness of exosome treatment in androgenetic alopecia: outcomes of a prospective study. Aesthetic Plastic Surgery 2024, DOI 10.1007/s00266-024-04332-3. Citation sous licence CC-BY.

completed the study and the follow-up period with no dropouts. No side effects or complications were observed immediately after exosome injection or during follow-up.

Citation complémentaire (inclusion)

This prospective study included 30 male patients, aged between 22 and 65, with hair type III–VI according to the Norwood-Hamilton scale. They agreed not to change their hairstyleandwouldnotundergoanyhaircareortreatment

Citation complémentaire (methode)

vertex points) were taken. After the imaging, the applica- tionwasperformed:Atotalof3 mLofexosomes(2 mLto the frontal and 1 mL to the vertex region) was injected using the napage technique (1010 extracellular vesicles in 1 mL). Patients were observed for possibleside effects for 1 h after the procedure. Patients were instructed not to wash their hair and avoid heavy activities for 1 day after

Ersan M, Ozer E, Akin O et al.. Effectiveness of exosome treatment in androgenetic alopecia: outcomes of a prospective study. Aesthetic Plastic Surgery 2024, DOI 10.1007/s00266-024-04332-3. Citation sous licence CC-BY.