Minoxidil topique 5 % face à Laser erbium-verre fractionné 1550 nm + minoxidil 5 %
1 essai les comparent directement, sur les mêmes patients. Voir Minoxidil topique 5 % · Voir Laser erbium-verre fractionné 1550 nm + minoxidil 5 %
Chez 30 hommes atteints d'alopécie androgénétique, ajouter le laser erbium-verre fractionné 1550 nm au minoxidil topique 5 % fait significativement mieux que le minoxidil seul, sur deux moitiés du crâne comparées. En 24 semaines, le nombre de cheveux par cm² passe de 96,58 à 147,12 côté laser contre 97,25 à 133,77 côté minoxidil seul, et l'épaisseur du cheveu de 50,93 à 67,28 µm contre 51,16 à 65,32 µm (Suchonwanit 2019). Un seul essai, de fiabilité modérée.
Suchonwanit 2019
Essai randomisé, risque de biais modéré. A randomized, investigator-blinded, controlled, split-scalp study of the efficacy and safety of a 1550-nm fractional erbium-glass laser, used in combination with topical 5% minoxidil versus 5% minoxidil alone, for the treatment of androgenetic alopecia
| Critère | Minoxidil topique 5 % | Laser erbium-verre fractionné 1550 nm + minoxidil 5 % | Écart |
|---|---|---|---|
| Densité capillaire totale | 97,25 → 133,77 cheveux par cm²Voir la citationtively(p=0.001). Bycomparison,forthemonotherapy, hair densityincreasedfrom97.25±15.91,atbaseline,to133.77± 19.42hairs/cm2,at24weeks(p=0.001),withthehairdiam- eter increasing from 51.16±14.53 to 65.32±16.42 μm, re- Citation complémentaire (significativite) The mean difference of the change in hair density, from baseline, was significantly higher for the combination than monotherapy at treatment weeks 16 (p=0.042), 20 (p= 0.001), and 24 (p=0.004), as shown in Fig. 1. For the hair Suchonwanit P, Rojhirunsakool S, Khunkhet S. A randomized, investigator-blinded, controlled, split-scalp study of the efficacy and safety of a 1550-nm fractional erbium-glass laser, used in combination with topical 5% minoxidil versus 5% minoxidil alone, for the treatment of androgenetic alopecia. Lasers in Medical Science 2019, DOI 10.1007/s10103-019-02783-8. Citation reproduite au titre du droit de courte citation (article L122-5 du Code de la propriété intellectuelle). | 96,58 → 147,12 cheveux par cm²Voir la citationcreased from 96.58±16.52, at baseline, to 147.12±18.19 Citation complémentaire (significativite) The mean difference of the change in hair density, from baseline, was significantly higher for the combination than monotherapy at treatment weeks 16 (p=0.042), 20 (p= 0.001), and 24 (p=0.004), as shown in Fig. 1. For the hair Suchonwanit P, Rojhirunsakool S, Khunkhet S. A randomized, investigator-blinded, controlled, split-scalp study of the efficacy and safety of a 1550-nm fractional erbium-glass laser, used in combination with topical 5% minoxidil versus 5% minoxidil alone, for the treatment of androgenetic alopecia. Lasers in Medical Science 2019, DOI 10.1007/s10103-019-02783-8. Citation reproduite au titre du droit de courte citation (article L122-5 du Code de la propriété intellectuelle). | Probablement réel |
| Diamètre de la tige pilaire | 51,16 → 65,32 µmVoir la citationtively(p=0.001). Bycomparison,forthemonotherapy, hair densityincreasedfrom97.25±15.91,atbaseline,to133.77± 19.42hairs/cm2,at24weeks(p=0.001),withthehairdiam- eter increasing from 51.16±14.53 to 65.32±16.42 μm, re- Citation complémentaire (significativite) py at treatment week 20 (p=0.032) and 24 (p=0.034), as Suchonwanit P, Rojhirunsakool S, Khunkhet S. A randomized, investigator-blinded, controlled, split-scalp study of the efficacy and safety of a 1550-nm fractional erbium-glass laser, used in combination with topical 5% minoxidil versus 5% minoxidil alone, for the treatment of androgenetic alopecia. Lasers in Medical Science 2019, DOI 10.1007/s10103-019-02783-8. Citation reproduite au titre du droit de courte citation (article L122-5 du Code de la propriété intellectuelle). | 50,93 → 67,28 µmVoir la citationhairs/cm2, at 24 weeks (p=0.001), with the hair diameter increasing from 50.93±13.59 to 67.28±15.63 μm, respec- Citation complémentaire (significativite) py at treatment week 20 (p=0.032) and 24 (p=0.034), as Suchonwanit P, Rojhirunsakool S, Khunkhet S. A randomized, investigator-blinded, controlled, split-scalp study of the efficacy and safety of a 1550-nm fractional erbium-glass laser, used in combination with topical 5% minoxidil versus 5% minoxidil alone, for the treatment of androgenetic alopecia. Lasers in Medical Science 2019, DOI 10.1007/s10103-019-02783-8. Citation reproduite au titre du droit de courte citation (article L122-5 du Code de la propriété intellectuelle). | Probablement réel |