Minoxidil topique 5 % face à Minoxidil 5 % le matin + finastéride topique 0,25 % le soir

percentage of subjects in Group A achieved a GPAS score of ≥2 in comparison with Groups B and C after both 3 and 6 months (month by the 3: 84% vs. 8% and 45%; month 6: 79% vs. 8% and 41%, respectively).

Citation complémentaire (inclusion)

Patients and Methods: Forty- two males, mean age 24 ± 3 years, with AGA (I– VII of Norwood- Hamilton Grading Scale), treatment naive or free from any therapy for at least 6 months, were enrolled and randomly assigned to three arm treatment groups (2:1:1): group A (n = 19, the subjects applied 5% MNX in the morning and F spray in the evening), group B (n = 12, the subjects applied F spray in the evening), and group C (n = 11, the subjects applied 5% MNX twice daily). The efficacy of treatments was

Rossi A, Caro G. Efficacy of the association of topical minoxidil and topical finasteride compared to their use in monotherapy in men with androgenetic alopecia: a prospective, randomized, controlled, assessor blinded, 3-arm, pilot trial. Journal of Cosmetic Dermatology 2024, DOI 10.1111/jocd.15953. Citation sous licence CC-BY.

percentage of subjects in Group A achieved a GPAS score of ≥2 in comparison with Groups B and C after both 3 and 6 months (month by the 3: 84% vs. 8% and 45%; month 6: 79% vs. 8% and 41%, respectively).

Citation complémentaire (inclusion)

Patients and Methods: Forty- two males, mean age 24 ± 3 years, with AGA (I– VII of Norwood- Hamilton Grading Scale), treatment naive or free from any therapy for at least 6 months, were enrolled and randomly assigned to three arm treatment groups (2:1:1): group A (n = 19, the subjects applied 5% MNX in the morning and F spray in the evening), group B (n = 12, the subjects applied F spray in the evening), and group C (n = 11, the subjects applied 5% MNX twice daily). The efficacy of treatments was

Rossi A, Caro G. Efficacy of the association of topical minoxidil and topical finasteride compared to their use in monotherapy in men with androgenetic alopecia: a prospective, randomized, controlled, assessor blinded, 3-arm, pilot trial. Journal of Cosmetic Dermatology 2024, DOI 10.1111/jocd.15953. Citation sous licence CC-BY.

density over time (158.2 12.5 and 183.5 15.3 hair/cm2 at T3 and ± ± T6 for Group A, 149.5 14.3 and 154.6 18.6 hair/cm2 at T3 and ± ± T6 for Group B, and 212.3 18.4 and 223.7 19.8 hair/cm2 at T3 ± ± and T6 for Group C) although it was statistically significant only in group A (Figure 2). The mean change in hair density from baseline was statistically different between group A (MNX F) and group B + (F) (p < 0.01) but no statistical differences were observed between group A (MNX F) and group C (MNX), both after 3 and 6 months.

Citation complémentaire (inclusion)

Patients and Methods: Forty- two males, mean age 24 ± 3 years, with AGA (I– VII of Norwood- Hamilton Grading Scale), treatment naive or free from any therapy for at least 6 months, were enrolled and randomly assigned to three arm treatment groups (2:1:1): group A (n = 19, the subjects applied 5% MNX in the morning and F spray in the evening), group B (n = 12, the subjects applied F spray in the evening), and group C (n = 11, the subjects applied 5% MNX twice daily). The efficacy of treatments was

Citation complémentaire (valeur)

At baseline, mean ± SE hair density was 101.9 ± 13.4, 136.6 ± 13.9, on and 185.0 16.7 hair/cm2, for group A (MNX F), group B (F), and Wiley ± +

Rossi A, Caro G. Efficacy of the association of topical minoxidil and topical finasteride compared to their use in monotherapy in men with androgenetic alopecia: a prospective, randomized, controlled, assessor blinded, 3-arm, pilot trial. Journal of Cosmetic Dermatology 2024, DOI 10.1111/jocd.15953. Citation sous licence CC-BY.

density over time (158.2 12.5 and 183.5 15.3 hair/cm2 at T3 and ± ± T6 for Group A, 149.5 14.3 and 154.6 18.6 hair/cm2 at T3 and ± ± T6 for Group B, and 212.3 18.4 and 223.7 19.8 hair/cm2 at T3 ± ± and T6 for Group C) although it was statistically significant only in group A (Figure 2). The mean change in hair density from baseline was statistically different between group A (MNX F) and group B + (F) (p < 0.01) but no statistical differences were observed between group A (MNX F) and group C (MNX), both after 3 and 6 months.

Citation complémentaire (inclusion)

Patients and Methods: Forty- two males, mean age 24 ± 3 years, with AGA (I– VII of Norwood- Hamilton Grading Scale), treatment naive or free from any therapy for at least 6 months, were enrolled and randomly assigned to three arm treatment groups (2:1:1): group A (n = 19, the subjects applied 5% MNX in the morning and F spray in the evening), group B (n = 12, the subjects applied F spray in the evening), and group C (n = 11, the subjects applied 5% MNX twice daily). The efficacy of treatments was

Citation complémentaire (valeur)

At baseline, mean ± SE hair density was 101.9 ± 13.4, 136.6 ± 13.9, on and 185.0 16.7 hair/cm2, for group A (MNX F), group B (F), and Wiley ± +

Rossi A, Caro G. Efficacy of the association of topical minoxidil and topical finasteride compared to their use in monotherapy in men with androgenetic alopecia: a prospective, randomized, controlled, assessor blinded, 3-arm, pilot trial. Journal of Cosmetic Dermatology 2024, DOI 10.1111/jocd.15953. Citation sous licence CC-BY.

density over time (158.2 12.5 and 183.5 15.3 hair/cm2 at T3 and ± ± T6 for Group A, 149.5 14.3 and 154.6 18.6 hair/cm2 at T3 and ± ± T6 for Group B, and 212.3 18.4 and 223.7 19.8 hair/cm2 at T3 ± ± and T6 for Group C) although it was statistically significant only in group A (Figure 2). The mean change in hair density from baseline was statistically different between group A (MNX F) and group B + (F) (p < 0.01) but no statistical differences were observed between group A (MNX F) and group C (MNX), both after 3 and 6 months.

Citation complémentaire (inclusion)

Patients and Methods: Forty- two males, mean age 24 ± 3 years, with AGA (I– VII of Norwood- Hamilton Grading Scale), treatment naive or free from any therapy for at least 6 months, were enrolled and randomly assigned to three arm treatment groups (2:1:1): group A (n = 19, the subjects applied 5% MNX in the morning and F spray in the evening), group B (n = 12, the subjects applied F spray in the evening), and group C (n = 11, the subjects applied 5% MNX twice daily). The efficacy of treatments was

Citation complémentaire (valeur)

At baseline, mean ± SE hair density was 101.9 ± 13.4, 136.6 ± 13.9, on and 185.0 16.7 hair/cm2, for group A (MNX F), group B (F), and Wiley ± +

Rossi A, Caro G. Efficacy of the association of topical minoxidil and topical finasteride compared to their use in monotherapy in men with androgenetic alopecia: a prospective, randomized, controlled, assessor blinded, 3-arm, pilot trial. Journal of Cosmetic Dermatology 2024, DOI 10.1111/jocd.15953. Citation sous licence CC-BY.

density over time (158.2 12.5 and 183.5 15.3 hair/cm2 at T3 and ± ± T6 for Group A, 149.5 14.3 and 154.6 18.6 hair/cm2 at T3 and ± ± T6 for Group B, and 212.3 18.4 and 223.7 19.8 hair/cm2 at T3 ± ± and T6 for Group C) although it was statistically significant only in group A (Figure 2). The mean change in hair density from baseline was statistically different between group A (MNX F) and group B + (F) (p < 0.01) but no statistical differences were observed between group A (MNX F) and group C (MNX), both after 3 and 6 months.

Citation complémentaire (inclusion)

Patients and Methods: Forty- two males, mean age 24 ± 3 years, with AGA (I– VII of Norwood- Hamilton Grading Scale), treatment naive or free from any therapy for at least 6 months, were enrolled and randomly assigned to three arm treatment groups (2:1:1): group A (n = 19, the subjects applied 5% MNX in the morning and F spray in the evening), group B (n = 12, the subjects applied F spray in the evening), and group C (n = 11, the subjects applied 5% MNX twice daily). The efficacy of treatments was

Citation complémentaire (valeur)

At baseline, mean ± SE hair density was 101.9 ± 13.4, 136.6 ± 13.9, on and 185.0 16.7 hair/cm2, for group A (MNX F), group B (F), and Wiley ± +

Rossi A, Caro G. Efficacy of the association of topical minoxidil and topical finasteride compared to their use in monotherapy in men with androgenetic alopecia: a prospective, randomized, controlled, assessor blinded, 3-arm, pilot trial. Journal of Cosmetic Dermatology 2024, DOI 10.1111/jocd.15953. Citation sous licence CC-BY.

ever only in group A (Figure 3A). The mean change in hair terminal density from baseline was statistically different between group A (MNX + F) and group B (F) (p < 0.05) but no statistical differences were observed between group A (MNX + F) and group C (MNX), both after 3 and 6 months. On the contrary, although it was possible

Citation complémentaire (inclusion)

Patients and Methods: Forty- two males, mean age 24 ± 3 years, with AGA (I– VII of Norwood- Hamilton Grading Scale), treatment naive or free from any therapy for at least 6 months, were enrolled and randomly assigned to three arm treatment groups (2:1:1): group A (n = 19, the subjects applied 5% MNX in the morning and F spray in the evening), group B (n = 12, the subjects applied F spray in the evening), and group C (n = 11, the subjects applied 5% MNX twice daily). The efficacy of treatments was

Rossi A, Caro G. Efficacy of the association of topical minoxidil and topical finasteride compared to their use in monotherapy in men with androgenetic alopecia: a prospective, randomized, controlled, assessor blinded, 3-arm, pilot trial. Journal of Cosmetic Dermatology 2024, DOI 10.1111/jocd.15953. Citation sous licence CC-BY.

ever only in group A (Figure 3A). The mean change in hair terminal density from baseline was statistically different between group A (MNX + F) and group B (F) (p < 0.05) but no statistical differences were observed between group A (MNX + F) and group C (MNX), both after 3 and 6 months. On the contrary, although it was possible

Citation complémentaire (inclusion)

Patients and Methods: Forty- two males, mean age 24 ± 3 years, with AGA (I– VII of Norwood- Hamilton Grading Scale), treatment naive or free from any therapy for at least 6 months, were enrolled and randomly assigned to three arm treatment groups (2:1:1): group A (n = 19, the subjects applied 5% MNX in the morning and F spray in the evening), group B (n = 12, the subjects applied F spray in the evening), and group C (n = 11, the subjects applied 5% MNX twice daily). The efficacy of treatments was

Rossi A, Caro G. Efficacy of the association of topical minoxidil and topical finasteride compared to their use in monotherapy in men with androgenetic alopecia: a prospective, randomized, controlled, assessor blinded, 3-arm, pilot trial. Journal of Cosmetic Dermatology 2024, DOI 10.1111/jocd.15953. Citation sous licence CC-BY.

The global photographic assessment score (GPAS) was sig- use; OA nificantly higher in Group A compared to Group B (p < 0.001) and articles Group C (p 0.05), both at 3 and 6 months (2.0 0.7 vs. 0.6 0.8 and < ± ± are 1.3 ± 0.6; respectively at month 6) (Figure 5). A significantly greater

Citation complémentaire (inclusion)

Patients and Methods: Forty- two males, mean age 24 ± 3 years, with AGA (I– VII of Norwood- Hamilton Grading Scale), treatment naive or free from any therapy for at least 6 months, were enrolled and randomly assigned to three arm treatment groups (2:1:1): group A (n = 19, the subjects applied 5% MNX in the morning and F spray in the evening), group B (n = 12, the subjects applied F spray in the evening), and group C (n = 11, the subjects applied 5% MNX twice daily). The efficacy of treatments was

Rossi A, Caro G. Efficacy of the association of topical minoxidil and topical finasteride compared to their use in monotherapy in men with androgenetic alopecia: a prospective, randomized, controlled, assessor blinded, 3-arm, pilot trial. Journal of Cosmetic Dermatology 2024, DOI 10.1111/jocd.15953. Citation sous licence CC-BY.

The global photographic assessment score (GPAS) was sig- use; OA nificantly higher in Group A compared to Group B (p < 0.001) and articles Group C (p 0.05), both at 3 and 6 months (2.0 0.7 vs. 0.6 0.8 and < ± ± are 1.3 ± 0.6; respectively at month 6) (Figure 5). A significantly greater

Citation complémentaire (inclusion)

Patients and Methods: Forty- two males, mean age 24 ± 3 years, with AGA (I– VII of Norwood- Hamilton Grading Scale), treatment naive or free from any therapy for at least 6 months, were enrolled and randomly assigned to three arm treatment groups (2:1:1): group A (n = 19, the subjects applied 5% MNX in the morning and F spray in the evening), group B (n = 12, the subjects applied F spray in the evening), and group C (n = 11, the subjects applied 5% MNX twice daily). The efficacy of treatments was

Rossi A, Caro G. Efficacy of the association of topical minoxidil and topical finasteride compared to their use in monotherapy in men with androgenetic alopecia: a prospective, randomized, controlled, assessor blinded, 3-arm, pilot trial. Journal of Cosmetic Dermatology 2024, DOI 10.1111/jocd.15953. Citation sous licence CC-BY.